Nasa Links to Bone Sites

NASA's Office of Physical and Biological Research -- tackling puzzles like osteoporosis through space research.

Gravity Hurts (So Good) -- Science@NASA article: Strange things can happen to the human body when people venture into space -- and the familiar pull of gravity vanishes.

National Space Biomedical Research Institute -- home page.

Q&A about osteoporosis -- from the American Medical Women's Association

Bone Loss research group -- webpage for the division of the National Space Biomedical Research Institute studying bone loss in space. Also has links to other divisions of NSBRI that deal with different medical issues related to space travel.

Prevention of Bone Loss During Manned Space Flight -- information about the Vanderbilt University research discussed in this article.

Sub-regional Assessment of Bone Loss -- fact sheet for an experiment on bone loss conducted on the International Space Station during Expedition Two. Information on this experiment from NASA's Johnson Space Center can also be found here .

Medical benefits of NASA research on bone loss -- information on how research to solve the mystery of bone loss in space helps to advance the treatment of osteoporosis.

A Boon for Bone Research -- a medical tool for measuring bone stiffness without using radiation was developed for researching bone loss in space, but it is also proving useful for diagnosing bone loss here on the ground.

Calcium Kinetics During Spaceflight -- technical information about how calcium is regulated in the body, both on the ground and in space. From NASA's Johnson Space Center.

Bone Function -- from the National Space Biomedical Research Institute.

Investigation of bone growth in space -- from the National Space Biomedical Research Institute.

Biotechnology research in microgravity -- from NASA's Marshall Space Flight Center

More links on osteoporosis -- from the National Aging Information Center

Related Publications

  • T.A. Bateman and S. Countryman. 2002. Osteoprotegerin and bone loss associated with spaceflight black triangle down. Drug Discov Today 15;7(8):456-457. [Abstract]
  • P.J. Kostenuik and V. Shalhoub. 2001. Osteoprotegerin: a physiological and pharmacological inhibitor of bone resorption. Curr Pharm Des 7(8):613-635. [Abstract]
  • P.J. Kostenuik, C. Capparelli, S. Morony, S. Adamu, G. Shimamoto, V. Shen, D.L. Lacey, and C.R. Dunstan. 2001. OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats. Endocrinology 142(10):4295-4304. [Abstract]
  • J.M. Brown, R.L. Vessella, P.J. Kostenuik, C.R. Dunstan, P.H. Lange, and E. Corey. 2001. Serum osteoprotegerin levels are increased in patients with advanced prostate cancer. Clin Cancer Res 7(10):2977-2983. [Abstract]
  • T.A. Bateman, C.R. Dunstan, D.L. Lacey, V.L. Ferguson, R.A. Ayers, and S.J. Simske. 2001. Osteoprotegerin ameliorates sciatic nerve crush induced bone loss. J Orthop Res 19(4):518-523. [Abstract]
  • E.R. Morey-Holton, B.P. Halloran, L.P. Garetto, and S.B. Doty. 2000. Animal housing influences the response of bone to spaceflight in juvenile rats. J Appl Physiol 88(4):1303-1309. [Abstract]


Web Sites


Web Site


Related Publications

  • T.F. Lang, G. Guglielmi, C. van Kuijk, A. De Serio, M. Cammisa, and H.K. Genant. 2002. Measurement of bone mineral density at the spine and proximal femur by volumetric quantitative computed tomography and dual-energy X-ray absorptiometry in elderly women with and without vertebral fractures. Bone 30(1):247-250. [Abstract]
  • D.R. Taaffe, J.A. Cauley, M. Danielson, M.C. Nevitt, T.F. Lang, D.C. Bauer, and T.B. Harris. 2001. Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study. J Bone Miner Res 16(7):1343-1352. [Abstract]
  • W. Gowin, P. Saparin, J. Kurths, and D. Felsenberg. 2001. Bone architecture assessment with measures of complexity. Acta Astronaut. 49(3-10):171-8. [Abstract]
  • T. Lang, J. Li, S. Harris, and H.K. Genant. 1999. Assessment of vertebral bone mineral density using volumetric quantitative computed tomography. J Comp Assist Tomography 23:130-137. [Abstract]
  • T. Lang, P. Augat, N. Lane, and H. Genant. 1998. Trochanteric hip fracture: strong association with spinal trabecular bone mineral density measured with quantitative computed tomography. Radiology 209:525-530. [Abstract]


Outreach Web Sites


Other Bone Health Experiments on Station